<i>FSHR</i> Gene Polymorphisms Causes Male Infertility

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FSHR Gene Polymorphisms Causes Male Infertility

Prior studies suggested sperm with damaged DNA permits fertilization but may lead to failure of embryo implantation following blastocyst formation. Quantitative correlations between DNA damage and risk of implantation failure have, however, so far not been performed. The aim of this study was to investigate two FSHR gene polymorphisms G919A (Ala307Thr) and A2039G (Asn680Ser) in Eastern Ukrainia...

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Genetic Causes of Male Infertility

Infertility is a major health problem today, affecting about 15.0% of couples trying to have a child. Impaired fertility of the male is causative in 20.0% of infertile couples and contributory in up to another 30.0-40.0%. Infertility already affects about 5.0-7.0% of the general male population and may further increase in the future, considering the apparent trend of declining sperm count in in...

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Single Nucleotide Polymorphisms in a Male Infertility- Related Gene CatSper

Objective To identify single nucleotide polymorphisms (SNPs) of human CatSper gene, the mouse homologous gene product, which plays a crucial role in mouse male sterility. Methods We demonstrated a systematic screening of SNPs in coding regions and flanking intronic regions of human CatSper gene in a sample subset from a total 210 male individuals by DNA sequencing. Then we used PCR single-stran...

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Causes and Consequences of Male Infertility

Introduction: Infertility has various and innumerable causes, which pointing them out one by one is difficult and out of the scope of this paper. Infertility causes are different between males and females, and each case requires a separate and thorough research. The present study aimed to identify the male infertility causes. Methods: This study was conducted using a qualitative method, which ...

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[Causes and Factors of Male Infertility].

The preservation of reproductive health of the population is an important factor of demographic policy of the state. According to some authors from 14 to 30% of couples of reproductive age suffer from infertility, malefactor in such marriages is detected in more than half of the cases. As you know, in recent years there has been a significant deterioration in the main indicators of reproductive...

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ژورنال

عنوان ژورنال: Open Journal of Genetics

سال: 2016

ISSN: 2162-4453,2162-4461

DOI: 10.4236/ojgen.2016.61001